Parkinson’s disease (PD) is one of the great, seemingly incurable plights of humanity. It is a late-onset disorder, usually developing in people over 60, that causes degeneration of the central nervous system, with serious impairments to the motor system. Tremors, muscle rigidity, slowness, difficulties in walking and mild hallucinations are some of the main symptoms of the disease. Depression, anxiety and, ultimately, dementia are all too well-known consequences to the millions of people affected worldwide. Current treatments for this condition are limited in their effectiveness and often come with problematic side-effects.

parkinson's-disease-symptoms
Parkinson’s disease disorders. Via Kentucky Neurology and Rehab

Leading PD researchers at King’s College in London have recently been exploring the possibility of using the ayahuasca vine—a plant traditionally brewed into a psychedelic tea in the Amazon rainforest—to treat the disease. There are fascinating reasons and some interesting early results for the possibility of ayahuasca helping in the fight against PD.

Firstly, it’s important to understand that the motor symptoms of PD are caused by a decrease in the production of dopamine in the brain’s basal ganglia. This is why the main treatment in the past 50 years has been a precursor of dopamine called levodopa. However, due to its heavy side effects, other medication is often considered. These are usually dopamine agonists, which are less effective, but with milder side effects, or monoamine oxidase B (MAO-B) inhibitors, which stop this enzyme from breaking down dopamine, but are, unfortunately, also handled difficultly by the human body.

Ayahuasca Vine
Ayahuasca Vine (Banisteriopsis caapi). Photo: Ben De Loenen

Interestingly, the ayahuasca vine (Banisteriopsis caapi) contains a potent inhibitor of MAO enzymes and therefore shares some similarity with some current PD medicines. The vine does not appear to produce the same heavy side-effects that its synthetic versions do. However, given its MAO inhibiting properties, chemicals in ayahuasca, such as harmine, can still present health risks when taken in combination with certain foods.

The psychedelic brew ayahuasca is typically made from boiling two plants. By inhibiting MAOs in the gut, the chemistry of the vine allows the powerful psychedelic molecule DMT from the second plant (Psychotria viridis) to enter the bloodstream. This allows the DMT to pass the blood-brain barrier instead of being broken down, giving ayahuasca its highly sought-after visionary properties.

The addition of DMT-containing plants as an admixture is more associated with the increased interest that this brew has received from the Western world than its original native purpose. Traditionally, ayahuasca brews often did not contain large quantities of the psychedelic agent, but seemingly were being consumed primarily for the healing effects of the MAOIs in the vine. Ayahuasca is referred to as “aya” (soul) – “wasca” (vine) by the Quechuan indigenous society of the Amazon.

harmin merck ayahuasca
Harmine, an isolate of the ayauhasca vine, was used in early PD-related treatments. Photo: movementdisorders.org

Ayahuasca has a history in PD-related research stretching back almost one hundred years. Louis Lewin, a German pharmacologist, looked into using Banisteriopsis caapi as a possible treatment for rigid-akinetic syndromes in the late 1920s. He was successful in isolating a key active agent of the vine, which he named banisterine (now known as harmine), and the subsequent studies showed improvements in rigidity, but inconclusive results with resolving tremor.

Since the 1930s, this substance had not been further tested as treatment for PD. Recently, however, Banisteriopsis caapi has seen renewed interest, this time by one of the most influential names in PD research – Andrew Lees. Professor Lees has since 1969 been fascinated by the life and work of psychonaut extraordinaire and the author of “Naked Lunch”, William Burroughs. Lees adopted Burroughs as his proverbial mentor and, to this day, credits him for the persistence to stick to the medical path Lees had chosen, but become disillusioned with during the course of his studies.

drinking ayahuasca
Cup of ayahuasca.

Eventually, Burroughs’ psychedelic adventures in the Amazon inspired Lees to follow in his footsteps. He cites heading to the Colombian rainforest and trying ayahuasca for the first time in his 60s as a revolutionary experience that gave him new insights into his research and disintegrated the blocks that were holding him from advancing.

This adventure resulted in a study he recently co-authored that reports improvements in motor disability in marmosets when harmine is administered. Although the study didn’t find an increase in locomotor activity nor any dyskinetic effects, the team of researchers concluded that Banisteriopsis caapi is “mildly antiparkinsonian” and that it doesn’t interfere with the levodopa-induced response.

In a previous study conducted by a team of Spanish and Ecuadorian researchers, similar conclusions were drawn from the response of mice which were administered with a soluble extract of Banisteriopsis caapi. The treatment seemed to lower anxiety-related behavior, although it did not induce neuroprotective effects concerning dopamine.

Current results indicate that, due to the absence of certain toxicities, harmine may be a beneficial supplement to any ongoing PD therapy. Still, more research is needed to properly verify the safety or the success of ayahuasca as a PD treatment.

Parkinson’s disease effects people all across the world, yet in some places more than others. According to a recent comprehensive meta-analysis, in North America, Europe and Australia, it is almost three times more common for people over 70 to suffer from this affliction than in Asia (a single epidemiological study conducted in South America finds lower prevalence in Buenos Aires; however, this one result cannot be generalized to the Latin American population).

An additional study of the population of USA residents points to a potential genetic reasoning, as the racial distribution is skewed toward Caucasians. Differences in lifestyle appear important, particularly in the levels of stress, which has been implicated in the progression of PD, and possibly is a risk factor in its development. Farmers are more likely to develop PD, which some researchers suggest may be due to pesticide exposure.

There are obviously many factors at play when trying to understand the cause and treatment of PD. A brew long used by indigenous people of the Amazon for healing many disorders has the potential to help alleviate the disease’s effects. While ayahuasca is currently illegal in many parts of the globe, this emerging PD research provides another reason why government authorities that have banned it, and jailed those who use it, need to seriously rethink their approach.

Xavier Francuski

Xavier Francuski

Born in Asia, grew up in Europe, lived in the Americas, Xavier's unrooted existence fuels his instinct for exploration. With a background in research psychology, he tries to reconcile the astounding nature of the realms beyond with what sense we can make of them in this one.
Xavier Francuski

40 COMMENTS

  1. I am a 47-year-old man. My Parkinson’s disease appeared at the age of 39. My symptoms, at the beginning, were fine tremors and rigidity with joint stiffness. I was taking entacapone with levodopa, carbidopa, and pramipexole. My Parkinson’s disease was under control, but not totally reversed. After countless hours of online research and trial & error. What worked for me was Parkinson’s disease herbal remedy I purchased from Best Health Herbal Centre. I only used the Parkinson’s disease herbal remedy for five weeks. Now my Parkinson’s disease is totally reversed, am totally free. I am so grateful for my success all thanks to Best Health Herbal Centre…..For more information visit their website ww w .besthealthherbalcentre. com

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  2. My husband will be 81 years old next month and was diagnosed with Parkinson’s disease 13 months ago. his main symptom were and rigidity or stiffness of his right-hand side.he also had some difficulty writing. The original diagnosis was confirmed three months later by a second neurologist. He was on one tablet of pramipexole (Sifrol), 0.25 mg three times a day. Four months ago his neurologist added Biperiden, 2 mg. he takes half a tablet of Biperiden three times a day. Since the original diagnosis, his stiffness has slowly increased. He lost touch with reality. Suspecting it was the medication I took him off the Siferol (with the doctor’s knowledge) and started him on PD natural herbal formula we ordered from GREEN HOUSE HERBAL CLINIC, I spoke to few people who used the treatment here in Canada and they all gave a positive response, his symptoms totally declined over a 6 weeks use of the Green House Parkinson’s disease natural herbal formula. He is now almost 81 and doing very well, the disease is totally reversed! (Visit their website www . Greenhouseherbalclinic . com) I am thankful to nature, herbs are truly gift from God. Share with friends!!

  3. In April last year, i started on natural parkinsons disease herbal treatments from RICH HERBS FOUNDATION, i am happy to report this PD herbal treatment worked very effectively. My parkinson is totally under control, i had a total decline in symptoms, the tremors, shaking, stiffness, congnition and speech problems stopped. Visit rich herbs foundation official web page ww w. richherbsfoundation .com. My family are amazed at the change and rapid improvement.

  4. I was diagnosed five years ago at the age of 51. I had symptoms for 3-4 years prior to that but did not know anything about Parkinson’s. I first noticed a slight twitch in my left hand, finger and thumb, which became pill rolling. We attended a lot of sports events and I would lose my balance in the moving crowd. I then started seeing a neurologist. I started falling a lot when losing my balance and had a hard time walking normal. I finally froze up in the doorway at church. I told my Neuro and he said that I had Parkinson’s. Started me on entacapone,levodopa, carbidopa, and pramipexole and I still didn’t feel or get better January 2017 my neurologist and I decided to go with natural treatment and was introduced to Green House Herbal Clinic natural Parkinson’s disease Herbal formula, i had a total decline of symptoms with this Parkinson’s Herbal formula treatment. Visit Green House Herbal Clinic official web-site ww w. greenhouseherbalclinic. com. The tremors, Shaking, Joint Stiffness and other symptoms has subsided.  I am very pleased with this treatment. I feel very well now and exercise regularly, sometimes i totally forget i ever had Parkinson’s,Don’t give up hope, fellow sufferers. Share with friends!!

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  6. Parkinson’s symptoms first appeared when I was 68. I noticed a vibration in right foot and then right hand. After about 18 months a shake and/or tremor. Twelve months later, shaking. My neurologist. Started me on entacapone,levodopa, carbidopa, and pramipexole to reduce symptoms and slow down progression but I could not tolerate them for long due to severe side effects. I decided to adopt a more natural approach and started on Parkinson’s Disease Herbal formula from Green House Herbal Clinic, the PD natural formula immensely helped my condition, i had a total recovery from Parkinson’s disease with this natural herbal formula treatment. Visit Green House Herbal Clinic official web site ww w. greenhouseherbalclinic. Weebly. com. I feel alive again! The tremors, Shaking, Joint Stiffness and other symptoms has subsided.  I am very pleased with this treatment. I feel very well now and exercise regularly, sometimes i totally forget i ever had Parkinson’s, My family are amazed at the change and rapid recovery from PD. since the procedure I enjoy walking the dog for my daily exercise. DON’T GIVE UP HOPE!!!

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  9. I am a 49-year-old man. My Parkinson’s disease appeared at the age of 47. My symptoms, at the beginning, were fine tremors and rigidity with joint stiffness. My neurologist prescribed entacapone with levodopa, carbidopa, and pramipexole. I opted not to go on prescription medicines but decided on using herbs instead, October 18, 2017 after being on the herbs you recommended, i had a total recovery from Parkinson’s disease with this natural herbal formula treatment. The tremors, Shaking, Joint Stiffness has subsided. When I stumbled upon you guys, it was just pure instinct. And from that day on it has been one of the best decisions I’ve made in my life. The caring that goes into explaining what herbs work for whatever ails me is astounding. In today’s world where so many are after a quick buck, selling without care, The Herbal Garden’s staffs amplifies the difference. I’m a believer in karma, and for generations to come, this is a herbal store that will be leaving it’s footprint in this world. Visit ThE HERBAL GARDENS official web site www. theherbalgardens. org A world of thanks to The Herbal Gardens!”

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  11. I am a 59-year-old woman. My Parkinson’s disease appeared at the age of 57. My symptoms, at the beginning, were fine tremors and rigidity with joint stiffness. My neurologist prescribed entacapone with levodopa, carbidopa, and pramipexole. I opted not to go on prescription medicines but decided on using herbs instead, October 18, 2017 after being on the herbs you recommended, i had a total recovery from Parkinson’s disease with this natural herbal formula treatment. The tremors, Shaking, Joint Stiffness has subsided. When I stumbled upon you guys, it was just pure instinct. And from that day on it has been one of the best decisions I’ve made in my life. The caring that goes into explaining what herbs work for whatever ails me is astounding. In today’s world where so many are after a quick buck, selling without care, Natural Herbal Garden’s staffs amplifies the difference. I’m a believer in karma, and for generations to come, this is a herbal store that will be leaving it’s footprint in this world. Visit NATURAL HERBAL GARDENS official web site http://www.naturalherbalgardens.com A world of thanks to The Natural Herbal Gardens!”

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  13. My symptoms started at the age of 46. My fingers on my left hand were stiff and were difficult to move. People noticed that my walk was not normal. I was often asked did I hurt. I noticed nothing different about my walk. It was difficult getting up from` a chair and getting out of a car. I was diagnosed a year later and i have to find a better solution and was introduced to try the help of herbal formula. I am now 59 tho and am fully cured from Parkinson’s disease.
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  18. My wife was diagnosed of Parkinson’s Disease at age 49. She had severe calf pain, muscle pain, tremors, slurred speech, frequent falls, loss of balance, difficulty in getting up from sitting position. She was put on Senemet for 6 months and then Siferol was introduced and replaced the Senemet. During this time span she was also diagnosed with dementia. She started having hallucinations, lost touch with reality. This year, our family doctor started her on Natural Herbal Gardens Parkinson’s Disease Herbal mixture, With the help of Natural Herbal Garden natural herbs we have been able to reverse her symptoms using herbs, which i feel has made the most difference. 1 month into the herbal treatment she improved dramatically. At the end of the full treatment course, the disease is totally under control. No case of dementia, hallucination, weakness, muscle pain or tremors. She  turned 56 today. i am glad to get my wife back
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  19. Diagnosed last June after almost a year of many, many specialists telling me they had no idea what was wrong. My symptoms were all non-motor, insomnia, leg pain that will not go away, and anxiety issues. Had a DAT scan and that was the test that verified PD.

    Started on Requip, had such bad fatigue that I had to quit that and then started on Sinemet, no changes too. My son purchased PD herbal remedy online from Best Health Herbal Centre. My son said (Best Health Herbal Centre) to him that the herbal remedy will reverse my PD under 6 weeks. So after using the PD herbal remedy for 6 weeks, my PD was totally reversed. No more major fatigue, insomnia is better, leg pain disappeared. I can walk 4 miles now without feeling pain.

    I am 64, was diagnosed at 63. I thought i will die with brain fog and fatigue, but Best Health Herbal Centre saved my life.
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  24. HERBAL

    Diagnosed last June after almost a year of many, many specialists telling me they had no idea what was wrong. My symptoms were all non-motor, insomnia, leg pain that will not go away, and anxiety issues. Had a DAT scan and that was the test that verified PD.

    Started on Requip, had such bad fatigue that I had to quit that and then started on Sinemet, no changes too. My son purchased PD herbal remedy online from Best Health Herbal Centre. My son said (Best Health Herbal Centre) to him that the herbal remedy will reverse my PD under 6 weeks. So after using the PD herbal remedy for 6 weeks, my PD was totally reversed. No more major fatigue, insomnia is better, leg pain disappeared. I can walk 4 miles now without feeling pain.

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  28. I had to find a better solution because things were getting out of hand,during my research i found review of surviver who used Total cure herbal foundation herbal formula,in no time i had to order mine which get to my address in four days delivery,the herbal formula cure me totally from this virus and all symptoms terminated.
    You can search for Total cure herbal foundation or contact them directly Totalcureherbalfoundation gmailcom

  29. Greetings all….. my name is FREYA BOWETT am from LIVERPOOL ( UNITED KINGDOM ) , i want to share this great and wonderful testimony to the general public on how i got cured from my sickness called ( HERPES ) by DR Ehimare healing herbal medicine , I have been suffering from (HERPES) for good 4 years now and I was almost going to the end of my life due to the constant pain and especially inches in my private part . all I have in my mind is let me just give up because life was no longer intestine to me any more , I just pray to God every day to accept my soul when ever I die, luckily to me , my kid sister ran to me that she found a doctor in the internet who can cure (HERPES , HEPATITIS B,CANCER, and HIV/AIDS ) she helped me out on everything, the great Dr Ehimare only ask for my Details and some items , so that he can prepare a Herbal medicine for me and send it to me in my country , which he did.. so after two days of getting the medicine and taking it as prescribe to me from him , I started getting more stronger my blood started flowing normally , i started experiencing changes all over my Body as the great DR Ehimare assured me that i should go for medical check up that i have been cured, so after some time i went to my doctor to confirmed if i have be finally healed , behold it was TRUE and i was very Happy ,so if you have HERPES , HEPATITIS B ,CANCER , HIV/AIDS or any kind of sickness you can contact him and also he do cast love spell , and any kind of spell you can think off or any illness get cured, i advice you all to contact him on Via mail at (drehimarespelltemple@gmail.com) And you can as well add him on WhatsApp +2348148343053 Good luck.

  30. I was suffering from HIV and HERPES until i met with Dr.Ezra who permanently cured me. Now that i am cured i decided to share my testimony on the internet. This is my story, i have been suffering from HIV/HERPES for some years now and during this period i was taking series of medications but none seems to be working on me, so few weeks ago i went on a search on the internet to see if i could get any information on how to get rid of this disease. As i was searching i came across a testimony of someone who was cured from Cancer of the breast by Dr.Ezra so quickly i contacted him without having a second thought and he assured me that he was going to cure me. So he told me how we are going to go about it, after all the procedures and remedy given to me by him few weeks later i started experiencing changes all over my body, and when i finally finish taking the medicine i went to my doctor to confirm if really i was cured then he conducted a text on me, and my result came out Negative. So friends if you are suffering from any kinds of disease no matter how long it has been just contact Dr.Ezra on this Email Address: drezrahealinghome@gmail.com you can also call or whatsapp him on this Tel.No: +2348116755255 he said he has a cure to all manner of disease. Sir i am indeed grateful for your kind gesture.

  31. I was diagnose April 17,2016 and find out I’m HIV positive.I was scared because there is no cure for HIV/AIDS but today some people still don’t believe that there is cure for HIV, it can only be cured through Africans root and herbs,and our doctor’s here in USA few of them know’s about the African herbal medicine can cure Hiv but they chooses to hide it from us just to make a sales of ARV DRUGS. I did a research online finding way to get rid of my disease,I saw a comment about a herbal doctor on internet Name Dr Alabi who has cured several disease with his powerful herbal medicine, I contacted him on whats-app, chat with him explain my self to him.He said he can cure hiv perfectly well , he gave me his request which i send to him. within 5 days he sent me the herbal medicine through ups courier delivering service And told me how to take the medicine for 3 weeks to get cured,I did for 3 weeks, within this 3 weeks i notice a very big change in my health and i new some thing great has happened then i went to confirm my result it was absolutely Negative.The doctor who new i was hiv positive was asking me how come i am negative, what did it took to get cure and were did i get this medicine from and how did i get rid of it I told him every thing about the herbal medicine that cure me. imagine doctor telling me not to let anyone know about it,I wasn’t shock though i knew they know about the herbal cure but chose to hide it in other to make sales on ARV DRUGS,if you are HIV positive please contact my savior dr.alabispellhome@gmail.com
    or WHATSAPP him through this number +2348115204568

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